United Kingdom

Position type:

Full time


£22,214 to £25,728 p.a.

24 Aug 2018
20 Sep 2018

Full details:

Reference number: LEE-FBSMB1145

Are you an early career researcher looking for a challenge?

Do you have a background in Virology?

Do you want to further your career in one of the UK’s leading research intensive Universities?


We are seeking a research technician to work on the hepatitis C virus (HCV) NS5A protein in the laboratory of Prof. Mark Harris. You will use a range of molecular virology approaches to study NS5A of HCV genotype 3 (GT3) .GT3 infection is of major concern as it exhibits high levels of resistance to the new direct acting antivirals that are used to treat HCV infection, and also results in a more rapid progression to chronic liver disease compared to other genotypes.

This MRC funded project seeks to understand both the mechanism of NS5A antiviral resistance and the role of the protein in the unique pathogenesis of GT3 infection. To achieve this, it will exploit recently developed GT3 culture systems, and perform functional analysis of clinical samples obtained in collaboration with the HCV Research UK Biobank.You will have a background in molecular biology and expertise in the study of viruses. You will join a team of researchers focusing on mechanisms of positive strand RNA virus replication and host-cell interactions. You will be organised and willing to work collaboratively as part of a team.

The University of Leeds and the Faculty of Biological Sciences are committed to providing equal opportunities for all and offer a range of family friendly policies. The University is a charter member of Athena SWAN (the national body that promotes gender equality in higher education), and the Faculty of Biological Sciences gained a Bronze award in 2014 and submitted an application for a Silver award in April 2017. We are proud to be an inclusive Faculty that values all staff, and are happy to consider job share applications and requests for flexible working arrangements from our employees. 

Our Athena SWAN webpage provides more information: http://www.fbs.leeds.ac.uk/equality-and-diversity/athena-swan/

To explore the post further or for any queries you may have, please contact: Professor Mark Harris Tel: +44 (0)113 343 5632, email: m.harris@leeds.ac.uk

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