Research Fellow in Immuno-oncology Bioinformatics and Predictive Modelling

University of Southampton

More jobs at University of Southampton


United Kingdom

Position type:

Full time


£29,799 to £33,518

23 Jul 2018
20 Aug 2018

Full details:

Reference number: SOU-1038018CM

An exciting opportunity has arisen in the newly inaugurated state-of-the-art Centre for Cancer Immunology for a Research Fellow focused on immune-oncology bioinformatics and predictive modelling in the laboratories of Professors T. Underwood and T. Elliott. They have been recently awarded a Centers Network Accelerator Award from Cancer Research UK in conjunction with the University of Oxford and an Advanced Clinician Scientist Fellowship from Cancer Research UK and the Royal College of Surgeons of England.The main goals of these awards are to monitor the evolving landscape of tumour antigens over the course of immunotherapy using mutanome, proteome and immunopeptidome analysis, and to understand and model the ecosystems of oesophageal cancer using single cell sequencing and organoid systems.  The successful candidate will join a dynamic team of researchers with existing data to enable immediate analysis.  This post will work closely with bioinformaticians, molecular biologists, clinicians, and other collaborators to better understand how tumour ecosystems determine responses to existing therapies and the efficacy of immunotherapy.

They are seeking a Research Fellow primarily in the area of bioinformatics but with a strong understanding of predictive modeling and machine learning. The ideal candidate will have earned their PhD. in an area such as bioinformatics, biostatistics, or computational biology, or from a cross-disciplinary program that included one of these areas of study. Essential skills required for this position include proficiency in a Unix/Linux environment and a statistical package (e.g. R or Matlab), as well as an additional programming language (e.g., python, perl, C++, etc).  Individuals with experience in any of these additional areas are strongly encouraged to apply: proteomics (labeled or label-free), transcriptomics (e.g. microarray and RNA-Seq), cancer biology, immunology, predictive modeling and machine learning.

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD.Prior to the qualification being awarded the title of Senior Research Assistant will be given.

This is a fixed-term appointment from October 2018 for 3 years in the first instance. Salary is commensurate with experience.

Interviews will be held on Friday, 7th September 2018. Shortlisted candidates will be contacted w/c 27th August 2018. 

The University of Southampton offers benefits associated with national insurance and pension payments. 

Informal enquiries should be directed to Prof Tim Underwood ( ).  More information on the research activities of the Underwood and Elliott labs can be found at and


Application procedure:

You should submit your completed online application form. The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Ita Holmes (Recruitment Team) on +44 (0) 23 8059 9002. Please quote reference 1038018CM on all correspondence.

The Faculty of Medicine holds an Athena SWAN Silver Award demonstrating commitment to equal opportunities and gender balance in the workplace. The Faculty recognises that applicants may seek flexible working patterns which will be considered as part of the recruitment process. For further information including key benefits designed to help maintain and support employees' well-being and work-life balance, please see our working with us website pages.

We aim to be an equal opportunities employer and welcome applications from all sections of the community. Please note that applications from agencies will not be accepted unless indicated in the job advert.

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