Research Fellow in Epitranscriptomics (m6A mRNA methylation) - School of Biosciences

University of Birmingham

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Town/City:

Birmingham


Position type:

Full time


Salary:

£30,942 - £42,792

12 Dec 2019
27 Jan 2020

Full details:

Reference number: BIR-190006CQ

Role Purpose:

To create new knowledge and research tools by undertaking research activities within the established research project. This project aims to establish what the biological function of m6A is in Sex lethal alternative splicing regulating sex determination and dosage compensation. This project uses the fruit-fly Drosophila as a model organism. The project will involve using the techniques of genetics and molecular biology including Crispr/Cas9 genome editing, immunohistochemistry, confocal microscopy, and some biochemical techniques. This project is funded by a BBSRC Grant as a collaboration between the University of Birmingham and Nottingham, and the Principal Investigator is Dr Matthias Soller, and the Principal Investigator in Nottingham is Prof. Rupert Fray.

 

 

Main Duties:

  • Develop research objectives, think about and engage in the intellectual aspects of the project, contributing to project direction and proposals for own or joint research, in collaboration with of Dr Soller in a creative and productive manner
  • Execute experiments to generate data, and analyse and interpret data for the project
  • Contribute with preliminary data and project progress to writing bids for research funding
  • Apply knowledge in a way which develops new intellectual understanding
  • Disseminate research findings for publication, research seminars etc. This includes contributing to writing research papers, attending conferences and presenting talks and posters, and periodic presentation of progress reports at group meetings
  • Supervise students on research related work and provide guidance to PhD students where appropriate to the discipline. This includes teaching research techniques and providing guidance as required
  • Contribute to developing new models, techniques and methods, and trouble shooting and optimising other protocols to ensure experiments run smoothly Undertake management/administration arising from research as required, e.g. contribute to writing reports, etc.
  • Contribute to Departmental/School research-related activities and research-related administration
  • Collect research data through a variety of research methods, including scientific experimentation and keeping up with the relevant literature 
  • Present research outputs, including drafting academic publications or parts thereof, for example at seminars and as posters *
  • Provide guidance, as required, to support staff and any students who may be assisting with the research *
  • Deal with problems that may affect the achievement of research objectives and deadlines* 
  • Participate in outreach activities to disseminate the findings from this project to the wider public

 

 

Person Specification:

  • First degree in Biology, considerable research experience and a PhD or a PhD near completion in biology, genetics, biochemistry or related discipline within the life sciences are required
  • High level analytical capability
  • Ability to communicate complex information clearly, e.g. in spoken English, periodic preparation of PowerPoint presentations for progress reports and manuscripts
  • Fluency in relevant models, techniques or methods and ability to contribute to developing new ones. Experience working with Drosophila genetics, cell culture, immunohistochemistry, molecular biology, biochemistry, confocal microscopy and imaging
  • Ability to assess resource requirements and use resources effectively 
  • Understanding of and ability to contribute to broader management/administration processes as required

 

This BBSRC funded fixed-term appointment is initially available for 12 months starting 1. April 2020

 

For information visit www.sollerlab.org and for informal enquiries please contact Dr Matthias Soller (m.soller@bham.ac.uk)

 

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